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3, so it absolutely was not likely that there was multicollinearity in the multiple linear regression styles. Furthermore, we done sensitivity analyses by using urinary creatinine concentration (log-remodeled) to be a covariate as an alternative to creatinine-altered urinary hefty steel concentrations and together with interaction conditions between either toxic heavy metals (As, Cd, and Pb) or Se; none of the urinary creatinine focus and also the interaction terms was statistically substantial, and Total associations involving urinary significant metals and blood pressure level didn't transform (Tables S1 and S2).
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Urinary As and Se have been detected in all samples, when the detection costs ended up ninety three% and ninety four% for Cd and Pb, respectively. The Cd and Pb concentrations with the members in whom these things weren't detected were being established at 50 percent with the detection limit worth.
This cross-sectional analyze examined 1899 Grown ups in four Asian nations around the check here world. Urinary concentrations of major metals had been measured by inductively coupled plasma mass spectrometry. A questionnaire study was administered relating to unique features.
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したがって、予防医療の実践においては、その介入の利益が害を上回ることを示す根拠が存在することが必要
Versions during the urinary concentrations of guide and selenium were being associated with hypertension at reduced levels of publicity/ingestion.
Desk six presents the effects of various linear regression analyses inspecting the associations amongst urinary major steel concentrations and blood pressure in all participants (covariates: place, age, intercourse, and BMI). Statistically substantial associations weren't observed involving urinary As concentrations and blood pressure. Urinary focus of Pb was positively linked to each SBP and DBP, while urinary Se concentration of Se was negatively associated with them. All values of VIF ended up under one.
東京大学医学部先進循環器病学講座 特任講師。医師。医学博士。総合内科専門医。循環器専門医。ライフワークとして継続してきた予防医学の研究・臨床を社会実装することを目指している。慶應義塾大学医学部卒業。 社外取締役 大西 勝也